Jordan said at a news conference ahead of the hearing that he was not surprised the FBI revoked the security clearances of two of the individuals testifying. “I find it incredible that evidence that one side has garnered is not going to be shared with the other side,” said Democratic Rep. “We can talk about the testimony, but right now, you’re not getting the testimony,” Jordan said. “The law has not determined they are whistleblowers. “These are not whistleblowers,” Plaskett shot back. Jordan said Allen wasn’t comfortable including Democrats in his interview and said Democrats aren’t entitled to all the evidence collected when it comes to whistleblowers. But much to the dismay of Democrats, Jordan would not budge on providing the interview transcript or video. Stacey Plaskett, the top Democrat on the weaponization subcommittee, pressed Jordan during the hearing on whether Democrats can get access to the testimony from Allen’s interview with GOP members of the committee. Democrats, on the other hand, raised concerns about their access to information about some of those claims and questioned the credibility of the individuals testifying.ĭel. But the first individuals who sat for closed-door interviews with Jordan’s subcommittee earlier this year, including two of the whistleblowers who will appear publicly at the hearing Thursday, became an early flashpoint in the panel’s investigation, with Democrats raising questions about their legitimacy as whistleblowers and the credibility of their testimony.ĭuring the hearing, Republicans framed the whistleblowers as courageous for coming forward with their claims and argued what they have to say is important. Jordan, an Ohio Republican, has long touted the allegations of what he claims are “dozens” of whistleblowers who serve as the basis for his committee’s assertions that the FBI and Justice Department have become increasingly politicized in recent years. At least two of those agents – Marcus Allen and Steve Friend – were among the individuals testifying before the panel on Thursday. The hearing came one day after the FBI said it revoked the security clearances of three agents who either attended the January 6 2021, riot at the US Capitol or espoused alternate theories about the Capitol attack, according to a letter the FBI sent the subcommittee on Wednesday, a copy of which was obtained by CNN. Further exploration of DNA minor groove-binding agents in the treatment of HCC appears warranted.Three self-described FBI whistleblowers, who are key to the Republican narrative that the FBI is weaponized against conservatives, testified at a House hearing Thursday, the latest escalation of Judiciary Chairman Jim Jordan’s investigation into allegations of discrimination and bias within the FBI. However, because of significant and prolonged hematologic toxicity, when given as a single dose every 6 weeks, further development of this drug in HCC is not possible. KW-2189 showed evidence of anti-tumor activity in HCC. Two responses were seen in patients enrolled at the higher dose, including one sustained CR. Due to continued significant hematologic toxicity in the next five patients enrolled at the lower dose the trial was closed to accrual. Other endpoints included toxicity, disease-free survival, and overall survival.ĭue to hematologic toxicity the dose of KW-2189 was reduced to 0.375 mg/m2 after 11 patients had been enrolled into the trial. The primary endpoint of the trial was objective regression. Patients received KW-2189 at a dose of 0.5 mg/m2 administered on day 1 of a 6-week cycle. KW-2189, a DNA minor groove-binding agent, has shown promising activity against HCC in preclinical evaluations.Ī phase II study was conducted to evaluate the activity of KW-2189 in patients with histologic or cytologic confirmed advanced or metastatic HCC who had no prior systemic therapy. Currently no effective therapies exist for patients with advanced or metastatic HCC. Hepatocellular carcinoma (HCC) is a common cancer in certain portions of the world.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |